Soma madness!

Let's imagine the perfect drug.

(This is part 2 of the hedonism series. Put your party hats on!)

First, it shouldn't have any unwanted side effects. No physical impairment (drunk), no addiction or physical dependence (heroin), no long term impact on your body (cancer from smoking), no bad trips, no risk of overdose, no withdrawal symptoms, no buildup of tolerance.

Thanks to advances in biochemistry, we know why these side effects occur. For example, a chemical called dynorphin blocks the reward pathway in your brain, inhibiting you from feeling the same pleasure over and over. If you use cocaine repeatedly, your brain makes more dynorphin and you won't get the same high you got when you started. Addiction is more complicated, but there's no reason why we can't figure out a cure.

So the perfect drug has no nasty side effects, but what can it do for you?

The pleasure drugs: These are the ones that directly stimulate the reward centers of your brain: new forms of heroin, oxycotin, morphine, drugs that wash away pain and turns your pleasure dial up beyond what is natural. It doesn't have to be a chemical substance either; scientists have successfully hooked up electrode to the spinal nerve of disabled patients and use it to trigger orgasms. If possible, electrical brain stimulation (wireheading) may provide a safer and cleaner high than chemicals.

But getting high is boring, one-dimensional. It's a solitary and selfish experience; you can't share it with other people in any meaningful way. Press a button, take a dose, and you'll be checking out of reality, floating through outer space, alone. There's not much else you can do when the intense artificial pleasure eclipses all other feelings. What might that do to your psyche? Look:

A portrait of loneliness: Kurt Cobain spent his last years struggling with heroin addiction; this was him on a good day.

The mood drugs: These drugs affect you in subtler, but more diverse ways. Unlike the pleasure pills, you'll stay grounded in reality, but your mood, personality and motivations are shifted in the designed direction.

Shown here in a common delivery device, caffeine is the second most popular drug in the world.

They can make a depressed person happier (Zoloft, Prozac), calm your anxieties and ease your stress;  they can make you friendlier (Ecstasy), more open and empathic, lower your inhibitions (alcohol); they can make you more motivated, focused (Ritalin, Adderall), raise your alertness (caffeine); they can make you feel safer and more secure, more trustful (oxytocin), increase your libido (testosterone), and even make you fall in love.

Yes, love; read the wireheading article and take note: "Repetition of these stimulations made the patient more communicative and flirtatious, and she ended by openly expressing her desire to marry the therapist." Dr. Paul Zak has also found link between the chemical oxytocin and feelings of social trust and attachment to lovers, to friends, to children, to God.

So you can become fitter, happier, more productive, comfortable, but is there an upper limit? That's what David Pearce asks, and he postulates a future where our level of well-being far exceeds what we feel today, a sublime happiness. What that would be like I can barely imagine. But I know that in the future, "not in the mood" will no longer be a hindrance; I can be in the mood, any mood, as long as I want to. That's freedom of self-expression.

But mood drugs are imprecise; they depend on the action of chemicals like serotonin that paints a broad spectrum of effects. It won't engage any higher-level mental concepts, only your gut-feelings. No wistful reminiscence, no bittersweet goodbyes, no victorious thrills. Though these drugs can prime you to enjoy living, you still have to go outside and actually do it. That brings us to the third kind...

The sensory drugs: These can make what you do feel better by enhancing and distorting your senses. In addition to their positive effects on mood, MDMA (Ecstasy) and methaqualone (quaaludes) can enhance your sensations of touch, making sex more pleasurable and intense. Mushrooms , mescaline, LSD, and other hallucinogens can change your perception in profound ways. Some color-blind people have even reported being able to see color while under the effects of LSD.

Depiction of the very first LSD trip: chemist Albert Hofmann biked home after taking ten times the regular dose.

So imagine that special occasion when you want the food and wine to taste a bit more delicious, the lights and the smile to look more vivid, the touch and the kiss to be more sensual, and everything basking in the soft glow of a heightened appreciation for reality. Think of a dance party, the music, the rhythm and movement. Think of running or swimming or biking and the incredible sense of freedom and speed you can get from just normal, everyday activities. You won't have to jump off mountains get that thrill!

You may have noticed that I've skipped over something between getting in the right mood and experiencing enhanced sensations. In this giant gap of the story is where we actually live our lives, where we work and learn and play. In here lies the difference between the false utopia of Brave New World, and the rich, varied, and fulfilling future you and I want to live in. And that's where I'll explore in the next part of Hedonism for the Transhuman.

Random thoughts and links:

• You know what I want? A reset button: something that can roll back your brain to a saved state. That way I can satisfy my curiosity on whatever I wish to try without worrying about any adverse and unforeseen effects. I get to keep all memories, but my emotional outlook, preferences, and goals can be safeguarded against unforeseen consequences. It's pure fantasy though.
  
  
• There's a major obstacle to what kind of chemicals we can put into our brains: the blood-brain barrier. It stops most cells, bacteria and large chemical molecules from entering the brain.
  
  
• Erowid.org has a comprehensive collection of facts, advice, and anecdotes about drug use.
  
  
• Neuroscientist Anjan Chatterjee has raised some ethical concerns about the future of pharmacological enhancements. I'll have to think about some of his objections to a drug-fueled society.